Anti-Hexokinase II antibody [EPR20839],Abcam,AB209847

Product Specifications Anti-Hexokinase II antibody [EPR20839] (ab209847) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-P, IP, WB in human, mouse, rat samples. Anti-Hexokinase II antibody [EPR20839] (ab209847) specifically detects Hexokinase II (UniProt ID: P52789; Molecular weight: 102kDa) and is sold in 100 µL and 1 mL selling sizes. Quality and Validation Abcam's high quality manufacturing and validation processes ensure Anti-Hexokinase II antibody [EPR20839] (ab209847) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-Hexokinase II antibody [EPR20839] (ab209847) has been confirmed by testing in knockout samples. Anti-Hexokinase II antibody [EPR20839] (ab209847) has been cited over 110 times in peer reviewed journals and is trusted by the scientific community. Related Products Conjugation-ready, carrier free format available for antibody clone EPR20839 - ab228819 . Antibody clone EPR20839 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 647, HRP ( ab237314 , ab237315 ). Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

ICC/IF, Flow Cyt (Intra), WB, IHC-P, IP

Platform ID

BAB204823460

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Hexokinase II antibody [EPR20839]
Cat. No.AB209847
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationICC/IF, Flow Cyt (Intra), WB, IHC-P, IP
ClonalityMonoclonal
Clone NumberEPR20839
Concentration0.579 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D-fructose 6-phosphate, respectively) (PubMed : 23185017, PubMed : 26985301, PubMed : 29298880). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate (PubMed : 29298880). Plays a key role in maintaining the integrity of the outer mitochondrial membrane by preventing the release of apoptogenic molecules from the intermembrane space and subsequent apoptosis (PubMed : 18350175). See full target information HK2

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