Anti-Histone H2A (symmetric di methyl R3)+Histone H4 (symmetric di methyl R3) antibody [EPR27303-14],Abcam,AB309354

Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Human, Mouse, Rat

Application

Flow Cyt (Intra), PepArr, IP, IHC-P, ICC/IF, IHC-Fr, WB

Platform ID

BAB143741529

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Histone H2A (symmetric di methyl R3)+Histone H4 (symmetric di methyl R3) antibody [EPR27303-14]
Cat. No.AB309354
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse, Rat
ApplicationFlow Cyt (Intra), PepArr, IP, IHC-P, ICC/IF, IHC-Fr, WB
ClonalityMonoclonal
Clone NumberEPR27303-14
Concentration0.457 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. See full target information H4C1 symmetric di methyl R3 Additional targets H2AC4 symmetric di methyl R3

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