Anti-Histone H2B antibody - ChIP Grade,Abcam,AB1790

What is this antibody validated in? Anti-Histone H2B antibody - ChIP Grade (ab1790) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF), ChIP in Arabidopsis thaliana, Cow, Human, Saccharomyces cerevisiae, Xenopus laevis samples. What is the molecular weight of Histone H2B? Anti-Histone H2B - ChIP Grade (ab1790) specifically detects a band for Histone H2B (UniProt: Q16778) at a molecular weight of 14kDa. Trusted by the scientific community Anti-Histone H2B - ChIP Grade (ab1790) was first used in a scientific publication in 2002 and has been cited over 250 times in peer-reviewed journals. Reviewed by scientists Anti-Histone H2B - ChIP Grade (ab1790) has over 25 independent reviews from customers.

Host

Rabbit

Reactivity

Cow, Human, Saccharomyces cerevisiae, Xenopus laevis, Arabidopsis thaliana

Application

IP, WB, ChIP, ICC/IF, IHC-P

Platform ID

BAB331485162

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Histone H2B antibody - ChIP Grade
Cat. No.AB1790
HostRabbit
IsotypeIgG
ReactivityCow, Human, Saccharomyces cerevisiae, Xenopus laevis, Arabidopsis thaliana
ApplicationIP, WB, ChIP, ICC/IF, IHC-P
ClonalityPolyclonal
Concentration0.9 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.. Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid. See full target information H2BC11

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