Anti-Histone H2B antibody [IGX4228R-1],Abcam,AB213225

This antibody is a recombinant chimeric antibody. Rabbit chimeric monoclonal antibody (Human Fab/ Rabbit Fc). For recommended secondary antibodies - Goat Anti-Rabbit IgG H&L (HRP) - ab205718 Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) - ab150077 Goat Anti-Rabbit IgG H&L (Alexa Fluor® 555) - ab150078 Goat Anti-Rabbit IgG H&L (Alexa Fluor® 647) - ab150079 Goat Anti-Rabbit IgG H&L (Alexa Fluor® 594) - ab150080

Host

Rabbit

Reactivity

Mouse, Cow, Human

Application

PepArr, ChIP, Dot, WB

Platform ID

BAB581510150

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Histone H2B antibody [IGX4228R-1]
Cat. No.AB213225
HostRabbit
IsotypeIgG1
ReactivityMouse, Cow, Human
ApplicationPepArr, ChIP, Dot, WB
ClonalityMonoclonal
Clone NumberIGX4228R-1
Concentration0.514 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.. Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid. See full target information H2BC12 Additional targets H2BC3,H2BC12L,,,,H2BC13,H2BC4,,H2BC18,H2BC17,H2BC21 acetyl K15,,H2BC11

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