Anti-Histone H3 (acetyl K18) antibody [EPR16595] - ChIP Grade,Abcam,AB177870

Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents .

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

ChIP-seq, Dot, PepArr, ICC/IF, IHC-P, WB, ChIP, ChIC/CUT&RUN-seq

Platform ID

BAB581810006

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Histone H3 (acetyl K18) antibody [EPR16595] - ChIP Grade
Cat. No.AB177870
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationChIP-seq, Dot, PepArr, ICC/IF, IHC-P, WB, ChIP, ChIC/CUT&RUN-seq
ClonalityMonoclonal
Clone NumberEPR16595
Concentration1.764 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. See full target information H3C1 acetyl K18

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