Anti-Histone H3 (acetyl K27) antibody - ChIP Grade,Abcam,AB4729
Anti-Histone H3 (acetyl K27) antibody - ChIP Grade (ab4729) is a rabbit polyclonal antibody and is validated for use in ChIP, ICC/IF, IHC-P, PepArr and WB. Anti-Histone H3 (acetyl K27) antibody - ChIP Grade (ab4729) was first used in a scientific publication in 1975 and has been cited over 2188 times in peer reviewed journals. It's performance in ChIP and Western Blot in human and mouse samples is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-Histone H3 (acetyl K27) antibody - ChIP Grade (ab4729) has high sensitivity and specificity. Anti-Histone H3 (acetyl K27) antibody - ChIP Grade (ab4729) has 85 independent reviews from customers. Anti-Histone H3 (acetyl K27) antibody - ChIP Grade (ab4729) specifically detects Histone H3 Acetyl-K27 (UniProt ID: P68431; Molecular weight: 16kDa) and is sold in 100 µg selling sizes. Top cited antibody for this target with >2500 citations and 70 five star abreviews. This antibody is useful in understanding H3K27ac's role in transcriptional activation and enhancer elements and is widely used as a marker in studies of post-translational modifications, embryonic genome activation and developmental biology. This antibody is crucial in cancer research and is widely used in studies of histone modifications involving histone acetyltransferases (HATs) and histone deacetylases (HDACs).
Host
Rabbit
Reactivity
Mouse, Rat, Cow, Human
Application
IHC-P, ICC/IF, ChIP, WB, PepArr
Platform ID
BAB519328747

Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-Histone H3 (acetyl K27) antibody - ChIP Grade
Cat. No.AB4729
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Cow, Human
ApplicationIHC-P, ICC/IF, ChIP, WB, PepArr
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. See full target information H3C1 acetyl K27
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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