Anti-Histone H3 (acetyl K4+K9+K14+K18+K23+K27) antibody [RM1045],Abcam,AB300641

What are recombinant multiclonals? Recombinant multiclonals are a mixture of recombinant antibodies co-expressed from a library of heavy and light chains. They offer several advantages including: - The sensitivity of polyclonal antibodies by recognising multiple epitopes - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production View our range of recombinant multiclonal antibodies . Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents .

Host

Rabbit

Reactivity

Rat, Mouse, Human

Application

WB, ICC, IP, Flow Cyt (Intra), PepArr, IHC-Fr, IHC-P, Dot

Platform ID

BAB269403711

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Histone H3 (acetyl K4+K9+K14+K18+K23+K27) antibody [RM1045]
Cat. No.AB300641
HostRabbit
IsotypeIgG
ReactivityRat, Mouse, Human
ApplicationWB, ICC, IP, Flow Cyt (Intra), PepArr, IHC-Fr, IHC-P, Dot
ClonalityMulticlonal
Clone NumberRM1045
Concentration0.477 mg/mL Batch dependent concentration
ImmunogenThis product was produced with the following immunogens:
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data The protein expressed by gene H3C1 is a core component of the nucleosome, which is essential for wrapping and compacting DNA into chromatin. This process restricts DNA accessibility to cellular machineries that use DNA as a template. Consequently, histones are central to transcription regulation, DNA repair, DNA replication, and chromosomal stability. DNA accessibility is regulated through a complex set of post-translational modifications of histones, known as the histone code, and through nucleosome remodeling. This supplementary information is collated from multiple sources and compiled automatically. See full target information H3C1 acetyl K4 + K9 + K14 + K18 + K23 + K27

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