Anti-Histone H3 (acetyl K9 + K14 + K18 + K23 + K27) antibody,Abcam,AB47915

What is this antibody validated in? Anti-Histone H3 (acetyl K9 + K14 + K18 + K23 + K27) antibody (ab47915) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP), ChIP, Dot Blot in Human samples. What is the molecular weight of Histone H3? Anti-Histone H3 (acetyl K9 + K14 + K18 + K23 + K27) (ab47915) specifically detects a band for Histone H3 (UniProt: P68431) at a molecular weight of 15kDa. Trusted by the scientific community Anti-Histone H3 (acetyl K9 + K14 + K18 + K23 + K27) (ab47915) was first used in a scientific publication in 2007 and has been cited over 120 times in peer-reviewed journals. Reviewed by scientists Anti-Histone H3 (acetyl K9 + K14 + K18 + K23 + K27) (ab47915) has over 5 independent reviews from customers.

Host

Rabbit

Reactivity

Human

Application

ChIP, Dot, WB

Platform ID

BAB894516157

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Histone H3 (acetyl K9 + K14 + K18 + K23 + K27) antibody
Cat. No.AB47915
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationChIP, Dot, WB
ClonalityPolyclonal
ImmunogenSynthetic Peptide within Human H3C1 acetyl K9 + K14 + K18 + K23 + K27. The exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.035% Sodium azide Constituents: Whole serum, 30% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data The protein expressed by gene H3C1 is a core component of the nucleosome, which is essential for wrapping and compacting DNA into chromatin. This process restricts DNA accessibility to cellular machineries that use DNA as a template. Consequently, histones are central to transcription regulation, DNA repair, DNA replication, and chromosomal stability. DNA accessibility is regulated through a complex set of post-translational modifications of histones, known as the histone code, and through nucleosome remodeling. This supplementary information is collated from multiple sources and compiled automatically. See full target information H3C1 acetyl K9 + K14 + K18 + K23 + K27

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