Anti-Histone H3 antibody [1B1B2] - Nuclear Marker and ChIP Grade,Abcam,AB195277

ab195277 can be used as a loading control for ChIP and Western blot experiments

Host

Mouse

Reactivity

Mouse, Human

Application

ICC/IF, WB, ChIP

Platform ID

BAB832034898

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Histone H3 antibody [1B1B2] - Nuclear Marker and ChIP Grade
Cat. No.AB195277
HostMouse
IsotypeIgG3
ReactivityMouse, Human
ApplicationICC/IF, WB, ChIP
ClonalityMonoclonal
Clone Number1B1B2
Concentration1.58 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human H3C1 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data The protein expressed by gene H3C1 is a core component of the nucleosome, which is essential for wrapping and compacting DNA into chromatin. This process restricts DNA accessibility to cellular machineries that use DNA as a template. Consequently, histones are central to transcription regulation, DNA repair, DNA replication, and chromosomal stability. DNA accessibility is regulated through a complex set of post-translational modifications of histones, known as the histone code, and through nucleosome remodeling. This supplementary information is collated from multiple sources and compiled automatically. See full target information H3C1

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