Anti-Histone H3 antibody [EPR21228] - Nuclear Marker,Abcam,AB213257

This product was made using synthetic libraries and phage display technology. This antibody is a recombinant chimeric antibody. Rabbit chimeric monoclonal antibody (Human Fab/ Rabbit Fc).

Host

Rabbit

Reactivity

Mouse, Cow, Human

Application

PepArr, WB, ChIP

Platform ID

BAB394566133

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Histone H3 antibody [EPR21228] - Nuclear Marker
Cat. No.AB213257
HostRabbit
IsotypeIgG1
ReactivityMouse, Cow, Human
ApplicationPepArr, WB, ChIP
ClonalityMonoclonal
Clone NumberEPR21228
Concentration0.465 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data The protein expressed by gene H3C1 is a core component of the nucleosome, which is essential for wrapping and compacting DNA into chromatin. This process restricts DNA accessibility to cellular machineries that use DNA as a template. Consequently, histones are central to transcription regulation, DNA repair, DNA replication, and chromosomal stability. DNA accessibility is regulated through a complex set of post-translational modifications of histones, known as the histone code, and through nucleosome remodeling. This supplementary information is collated from multiple sources and compiled automatically. See full target information H3C1

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