Anti-Histone H3 antibody - Nuclear Marker and ChIP Grade,Abcam,AB1791

Anti-Histone H3 antibody - Nuclear Marker and ChIP Grade (ab1791) is a rabbit polyclonal antibody and is validated for use in ChIP, ICC/IF, IHC-P, IP and WB. Anti-Histone H3 antibody - Nuclear Marker and ChIP Grade (ab1791) was first used in a scientific publication in 1987 and has been cited over 4739 times in peer reviewed journals. It's performance in Western blot and ChIP in human and mouse samples is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-Histone H3 antibody - Nuclear Marker and ChIP Grade (ab1791) has high sensitivity and specificity. Anti-Histone H3 antibody - Nuclear Marker and ChIP Grade (ab1791) has 230 independent reviews from customers. Anti-Histone H3 antibody - Nuclear Marker and ChIP Grade (ab1791) specifically detects Histone H3 (UniProt ID: P68431; Molecular weight: 16kDa) and is sold in 100 µg and 250 µg selling sizes. Top cited antibody for this target with >5000 citations and >150 five star abreviews. Key marker for researchers studying chromatin structure, epigenetic regulation and histone modifications. This antibody can use used as a control in cancer research, particularly in understanding histone mutations in various tumors and is widely used in studies of gene expression, DNA repair and cell cycle regulation.

Host

Rabbit

Reactivity

Mouse, Rat, Human, Saccharomyces cerevisiae, Xenopus laevis, Arabidopsis thaliana, Drosophila melanogaster, Indian muntjac, Schizosaccharomyces pombe

Application

ChIP, IP, IHC-P, ICC/IF, WB

Platform ID

BAB957097368

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Histone H3 antibody - Nuclear Marker and ChIP Grade
Cat. No.AB1791
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human, Saccharomyces cerevisiae, Xenopus laevis, Arabidopsis thaliana, Drosophila melanogaster, Indian muntjac, Schizosaccharomyces pombe
ApplicationChIP, IP, IHC-P, ICC/IF, WB
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. See full target information H3C1

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