Anti-Histone H3 antibody [mAbcam 24834] - Nuclear Loading Control and ChIP Grade,Abcam,AB24834

What is this antibody validated in? Anti-Histone H3 antibody [mAbcam 24834] - Nuclear Loading Control and ChIP Grade (ab24834) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP), ChIP in Human, Mouse, Rat samples. What is the molecular weight of Histone H3? Anti-Histone H3 [mAbcam 24834] - Nuclear Loading Control and ChIP Grade (ab24834) is often used as a loading control in Western blot. It specifically detects a band for Histone H3 (UniProt: P68431) at a molecular weight of 15kDa. Trusted by the scientific community Anti-Histone H3 [mAbcam 24834] - Nuclear Loading Control and ChIP Grade (ab24834) was first used in a scientific publication in 2005 and has been cited over 50 times in peer-reviewed journals. Reviewed by scientists Anti-Histone H3 [mAbcam 24834] - Nuclear Loading Control and ChIP Grade (ab24834) has over 5 independent reviews from customers. Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]

Host

Mouse

Reactivity

Mouse, Rat, Human

Application

WB, ChIP

Platform ID

BAB332084874

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Histone H3 antibody [mAbcam 24834] - Nuclear Loading Control and ChIP Grade
Cat. No.AB24834
HostMouse
IsotypeIgG3
ReactivityMouse, Rat, Human
ApplicationWB, ChIP
ClonalityMonoclonal
Clone NumbermAbcam 24834
Concentration1 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.5 Preservative: 0.02% Sodium azide Constituents: PBS, 6.97% L-Arginine
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data The protein expressed by gene H3C1 is a core component of the nucleosome, which is essential for wrapping and compacting DNA into chromatin. This process restricts DNA accessibility to cellular machineries that use DNA as a template. Consequently, histones are central to transcription regulation, DNA repair, DNA replication, and chromosomal stability. DNA accessibility is regulated through a complex set of post-translational modifications of histones, known as the histone code, and through nucleosome remodeling. This supplementary information is collated from multiple sources and compiled automatically. See full target information H3C1

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