Anti-Histone H3 (beta-hydroxybutyryl K23) antibody,Abcam,AB241460

Host

Rabbit

Reactivity

Human

Application

ChIP, WB

Platform ID

BAB457147344

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Histone H3 (beta-hydroxybutyryl K23) antibody
Cat. No.AB241460
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationChIP, WB
ClonalityPolyclonal
Concentration0.12 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human H3C1 beta-hydroxybutyryl K23. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data The protein expressed by gene H3C1 is a core component of the nucleosome, which is essential for wrapping and compacting DNA into chromatin. This process restricts DNA accessibility to cellular machineries that use DNA as a template. Consequently, histones are central to transcription regulation, DNA repair, DNA replication, and chromosomal stability. DNA accessibility is regulated through a complex set of post-translational modifications of histones, known as the histone code, and through nucleosome remodeling. This supplementary information is collated from multiple sources and compiled automatically. See full target information H3C1 beta-hydroxybutyryl K23

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