Anti-Histone H3 (di methyl K4) antibody,Abcam,AB272142

Host

Rabbit

Reactivity

Human, Caenorhabditis elegans

Application

WB, ICC/IF, ChIP, Dot

Platform ID

BAB144841001

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Histone H3 (di methyl K4) antibody
Cat. No.AB272142
HostRabbit
IsotypeIgG
ReactivityHuman, Caenorhabditis elegans
ApplicationWB, ICC/IF, ChIP, Dot
ClonalityPolyclonal
ImmunogenSynthetic Peptide within Human H3C1 di methyl K4. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.01% Sodium azide Constituents: 30% Glycerol (glycerin, glycerine), 0.88% Sodium chloride, 0.424% Potassium phosphate solution
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data The protein expressed by gene H3C1 is a core component of the nucleosome, which is essential for wrapping and compacting DNA into chromatin. This process restricts DNA accessibility to cellular machineries that use DNA as a template. Consequently, histones are central to transcription regulation, DNA repair, DNA replication, and chromosomal stability. DNA accessibility is regulated through a complex set of post-translational modifications of histones, known as the histone code, and through nucleosome remodeling. This supplementary information is collated from multiple sources and compiled automatically. See full target information H3C1 di methyl K4

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