Anti-Histone H3 (di methyl K4) antibody - ChIP Grade,Abcam,AB7766
For detection of Histone H3 specifically methylated at position Lys 4. This antibody was used in a screen by Dover et al, (2002) to isolate yeast mutants that are unable to methylate Lysine 4. In immunofluorescence, this antibody detects foci in the nucleus that are non-colocalising with condensed chromatin. The perinuclear and perinucleolar heterochromatin are not stained with this antibody. Learn about ChIP assay kits, other ChIP antibodies, protocols and more in the ChIP assay guide.
Host
Rabbit
Reactivity
Mouse, Rat, Cow, Human
Application
ICC/IF, PepArr, WB, ChIP
Platform ID
BAB457347248
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data The protein expressed by gene H3C1 is a core component of the nucleosome, which is essential for wrapping and compacting DNA into chromatin. This process restricts DNA accessibility to cellular machineries that use DNA as a template. Consequently, histones are central to transcription regulation, DNA repair, DNA replication, and chromosomal stability. DNA accessibility is regulated through a complex set of post-translational modifications of histones, known as the histone code, and through nucleosome remodeling. This supplementary information is collated from multiple sources and compiled automatically. See full target information H3C1 di methyl K4
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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