Anti-Histone H3 (di methyl K9) antibody [mAbcam 1220] - ChIP Grade,Abcam,AB1220

Anti-Histone H3 (di methyl K9) antibody [mAbcam 1220] - ChIP Grade (ab1220) is a House Mouse Monoclonal antibody and is validated for use in ChIP, Dot, ELISA, ICC/IF, IHC-P, WB in human samples. Anti-Histone H3 (di methyl K9) antibody [mAbcam 1220] - ChIP Grade (ab1220) has been cited over 961 times in peer reviewed journals and is trusted by the scientific community. Abcams high quality validation processes ensure Anti-Histone H3 (di methyl K9) antibody [mAbcam 1220] - ChIP Grade (ab1220) has high sensitivity and specificity. Anti-Histone H3 (di methyl K9) antibody [mAbcam 1220] - ChIP Grade (ab1220) has 71 independent reviews from customers. Anti-Histone H3 (di methyl K9) antibody [mAbcam 1220] - ChIP Grade (ab1220) specifically detects Histone H3 Di Methyl-K9 (UniProt ID: P68431; Molecular weight: 15kDa) and is sold in 100 ug selling sizes. Antibody clone mAbcam 1220 is also available pre-conjugated to a variety of labels for your convenience - HRP, Alexa Fluor® 488, Alexa Fluor® 647 ( ab62168 , ab2385 , ab23851). Histone H3 (di methyl K9), also known as H3K9me2, is an important epigenetic modification associated with gene silencing and heterochromatin formation. This anti histone H3 antibody detecting H3K9me2 is an essential tool for studying this modification's role in transcriptional repression and chromatin structure. Abnormal H3K9me2 levels are linked to various diseases, including cancer and neurological disorders. Monitoring di methyl K9 modifications can provide valuable insights into disease mechanisms and potential therapeutic targets. Learn about ChIP assay kits, other ChIP antibodies, and more in the ChIP assay guide . ChIP protocols: ChIP protocol for cross-linking ChIP (X-ChIP) Native ChIP protocol Chromatin preparation from tissues for ChIP ChIP troubleshooting ChIP tips and tricks guide Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]

Host

Mouse

Reactivity

Drosophila melanogaster, Rice, Cow, Human, Arabidopsis thaliana

Application

WB, ChIP, ELISA, Dot, ICC/IF, IHC-P

Platform ID

BAB832434706

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Histone H3 (di methyl K9) antibody [mAbcam 1220] - ChIP Grade
Cat. No.AB1220
HostMouse
IsotypeIgG2a
ReactivityDrosophila melanogaster, Rice, Cow, Human, Arabidopsis thaliana
ApplicationWB, ChIP, ELISA, Dot, ICC/IF, IHC-P
ClonalityMonoclonal
Clone NumbermAbcam 1220
Concentration1 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 6.97% L-Arginine
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. See full target information H3C1 di methyl K9

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