Anti-Histone H3 (di methyl R8) antibody,Abcam,AB194692

Host

Rabbit

Reactivity

Human

Application

ICC/IF, Dot, WB

Platform ID

BAB144940953

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Histone H3 (di methyl R8) antibody
Cat. No.AB194692
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationICC/IF, Dot, WB
ClonalityPolyclonal
Concentration0.6 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human H3-4 di methyl R8. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.3 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. See full target information H3C1 Additional targets H3C1

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