Anti-Histone H3 (mono methyl K4) antibody - ChIP Grade,Abcam,AB8895

Anti-Histone H3 (mono methyl K4) antibody - ChIP Grade (ab8895) is a rabbit polyclonal antibody and is validated for use in ChIP, ICC/IF, IHC-P and WB. Anti-Histone H3 (mono methyl K4) antibody - ChIP Grade (ab8895) was first used in a scientific publication in 2003 and has been cited over 1122 times in peer reviewed journals. It's performance in ChIP in human, mouse and rat samples is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-Histone H3 (mono methyl K4) antibody - ChIP Grade (ab8895) has high sensitivity and specificity. Anti-Histone H3 (mono methyl K4) antibody - ChIP Grade (ab8895) has 58 independent reviews from customers. Anti-Histone H3 (mono methyl K4) antibody - ChIP Grade (ab8895) specifically detects Histone H3 Mono Methyl-K4 (UniProt ID: P68431; Molecular weight: 16kDa) and is sold in 50 µg selling sizes. Top cited antibody for this target with >1000 citations. A highly cited Histone H3 mono methyl K4 antibody, essential for studying epigenetic modifications and gene activation. This antibody is crucial in chromatin structure research, particularly in understanding the role of H3K4me1 in transcription regulation. It is widely used in as a marker for histone methylation and enhancer regions.

Host

Rabbit

Reactivity

Cow, Human, Mouse, Rat

Application

IHC-P, ICC/IF, ChIP, WB

Platform ID

BAB770053399

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Histone H3 (mono methyl K4) antibody - ChIP Grade
Cat. No.AB8895
HostRabbit
IsotypeIgG
ReactivityCow, Human, Mouse, Rat
ApplicationIHC-P, ICC/IF, ChIP, WB
ClonalityPolyclonal
Concentration0.8 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. See full target information H3C1 mono methyl K4

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