Anti-Histone H3 (phospho S10 + T11) antibody [E173],Abcam,AB32107

What is this antibody validated in? Anti-Histone H3 (phospho S10 + T11) antibody [E173] (ab32107) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF), ELISA, Dot Blot in Human, Mouse samples. What is the molecular weight of Histone H3? Anti-Histone H3 (phospho S10 + T11) [E173] (ab32107) specifically detects a band for Histone H3 (UniProt: Q16695) at a molecular weight of 15kDa. Trusted by the scientific community Anti-Histone H3 (phospho S10 + T11) [E173] (ab32107) was first used in a scientific publication in 2006 and has been cited over 50 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [E173] also available for your convenience: ab32107, Alexa Fluor® 647 - ab200523 , Alexa Fluor® 488 - ab200614 , HRP - ab200616 , Carrier free - ab239803 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Human

Application

WB, ICC/IF, Dot, ELISA, IHC-P, IP

Platform ID

BAB582809526

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Histone H3 (phospho S10 + T11) antibody [E173]
Cat. No.AB32107
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationWB, ICC/IF, Dot, ELISA, IHC-P, IP
ClonalityMonoclonal
Clone NumberE173
Concentration0.1 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data The protein expressed by gene H3C1 is a core component of the nucleosome, which is essential for wrapping and compacting DNA into chromatin. This process restricts DNA accessibility to cellular machineries that use DNA as a template. Consequently, histones are central to transcription regulation, DNA repair, DNA replication, and chromosomal stability. DNA accessibility is regulated through a complex set of post-translational modifications of histones, known as the histone code, and through nucleosome remodeling. This supplementary information is collated from multiple sources and compiled automatically. See full target information H3C1 phospho S10 + T11

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