Anti-Histone H3 (phospho S10) antibody,Abcam,AB183626

Host

Rabbit

Reactivity

Mouse, Rat, Human, Zebrafish

Application

ICC/IF, IHC-P, IP, WB, ChIP, IHC - Wmt

Platform ID

BAB145240809

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Histone H3 (phospho S10) antibody
Cat. No.AB183626
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human, Zebrafish
ApplicationICC/IF, IHC-P, IP, WB, ChIP, IHC - Wmt
ClonalityPolyclonal
Concentration0.19 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human H3C1 phospho S10. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.025% Proclin 300 Constituents: PBS, 20% Glycerol (glycerin, glycerine), 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data The protein expressed by gene H3C1 is a core component of the nucleosome, which is essential for wrapping and compacting DNA into chromatin. This process restricts DNA accessibility to cellular machineries that use DNA as a template. Consequently, histones are central to transcription regulation, DNA repair, DNA replication, and chromosomal stability. DNA accessibility is regulated through a complex set of post-translational modifications of histones, known as the histone code, and through nucleosome remodeling. This supplementary information is collated from multiple sources and compiled automatically. See full target information H3C1 phospho S10

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