Anti-Histone H3 (phospho S10) antibody,Abcam,AB5176

What is this antibody validated in? Anti-Histone H3 (phospho S10) antibody (ab5176) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB) in Human samples. What is the molecular weight of Histone H3? Anti-Histone H3 (phospho S10) (ab5176) specifically detects a band for Histone H3 (UniProt: P68431) at a molecular weight of 17kDa. Trusted by the scientific community Anti-Histone H3 (phospho S10) (ab5176) was first used in a scientific publication in 2004 and has been cited over 320 times in peer-reviewed journals. Reviewed by scientists Anti-Histone H3 (phospho S10) (ab5176) has over 55 independent reviews from customers.

Host

Rabbit

Reactivity

Human

Application

WB, ICC

Platform ID

BAB770253303

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Histone H3 (phospho S10) antibody
Cat. No.AB5176
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationWB, ICC
ClonalityPolyclonal
Concentration0.9 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. See full target information H3C1 phospho S10

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