Anti-Histone H3 (tri methyl K36) antibody - ChIP Grade,Abcam,AB9050
Anti-Histone H3 (tri methyl K36) antibody - ChIP Grade (ab9050) is a rabbit polyclonal antibody and is validated for use in ChIP, ICC/IF, WB in cow, human, saccharomyces cerevisiae samples. Anti-Histone H3 (tri methyl K36) antibody - ChIP Grade (ab9050) has been cited over 975 times in peer reviewed journals and is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-Histone H3 (tri methyl K36) antibody - ChIP Grade (ab9050) has high sensitivity and specificity. Anti-Histone H3 (tri methyl K36) antibody - ChIP Grade (ab9050) has 64 independent reviews from customers. Anti-Histone H3 (tri methyl K36) antibody - ChIP Grade (ab9050) specifically detects Histone H3 Tri Methyl-K36 (UniProt ID: P68431; Molecular weight: 15kDa) and is sold in 100 µg selling sizes. H3K36me3 is a crucial epigenetic modification that involves the tri-methylation of lysine 36 on Histone H3, playing a significant role in gene regulation and DNA repair. Utilizing our tri methyl K36 antibody can significantly enhance the detection and study of this modification. Research indicates that H3K36me3 is associated with various cancers, making it a vital target for understanding disease mechanisms and developing new therapeutic strategies. Abnormal H3K36me3 levels are linked to cancer progression and poor prognosis. Studying H3K36me3 modifications can also provide insights into potential therapeutic targets for conditions like congenital heart defects and neurological disorders. For detection of methylated histone H3. Learn about ChIP assay kits, other ChIP antibodies, protocols and more in the ChIP assay guide .
Host
Rabbit
Reactivity
Cow, Human
Application
ICC/IF, WB, ChIP
Platform ID
BAB458046912

Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-Histone H3 (tri methyl K36) antibody - ChIP Grade
Cat. No.AB9050
HostRabbit
IsotypeIgG
ReactivityCow, Human
ApplicationICC/IF, WB, ChIP
ClonalityPolyclonal
Concentration0.8 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. See full target information H3C1 tri methyl K36
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
Request a product
Please provide the required information below so that we can quickly source your products.
