Anti-Histone H3 (tri methyl K9) antibody - ChIP Grade,Abcam,AB8898

Anti-Histone H3 (tri methyl K9) antibody - ChIP Grade (ab8898) is a rabbit polyclonal antibody and is validated for use in ChIP, ICC/IF, IHC-P and WB. Anti-Histone H3 (tri methyl K9) antibody - ChIP Grade (ab8898) was first used in a scientific publication in 2003 and has been cited over 1737 times in peer reviewed journals. It's performance in ChIP, Western Blot, IHC in human, mouse and rat samples is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-Histone H3 (tri methyl K9) antibody - ChIP Grade (ab8898) has high sensitivity and specificity. Anti-Histone H3 (tri methyl K9) antibody - ChIP Grade (ab8898) has 91 independent reviews from customers. Anti-Histone H3 (tri methyl K9) antibody - ChIP Grade (ab8898) specifically detects Histone H3 Tri Methyl-K9 (UniProt ID: P68431; Molecular weight: 16kDa) and is sold in 100 µg selling sizes. Top cited antibody for this target with >2000 citations and >60 five star abreviews. Key target to study histone H3 trimethylation, epigenetic regulation and chromatin structure. This antibody is crucial in cancer research, particularly in understanding H3K9me3's role in gene silencing and heterochromatin formation and is widely used in studies of transcriptional repression and histone modifications involving histone methyltransferases. Key histone marker that has been implicated in both transcriptional activation and silencing.

Host

Rabbit

Reactivity

Mouse, Cow, Human

Application

IHC-P, ICC/IF, ChIP, WB

Platform ID

BAB770653111

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Histone H3 (tri methyl K9) antibody - ChIP Grade
Cat. No.AB8898
HostRabbit
IsotypeIgG
ReactivityMouse, Cow, Human
ApplicationIHC-P, ICC/IF, ChIP, WB
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. See full target information H3C1 tri methyl K9

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