Anti-Histone H4 (acetyl K5 + K8 + K12) antibody,Abcam,AB233193

Host

Rabbit

Reactivity

Human

Application

ChIP-seq, WB, Dot, ICC/IF, ChIP

Platform ID

BAB895915485

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Histone H4 (acetyl K5 + K8 + K12) antibody
Cat. No.AB233193
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationChIP-seq, WB, Dot, ICC/IF, ChIP
ClonalityPolyclonal
Concentration1.05 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human H4C1 acetyl K8 + K12 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide, 0.05% Proclin 300 Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. See full target information H4C1 acetyl K8 + K12

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