Anti-Histone H4 antibody - ChIP Grade,Abcam,AB7311

What is this antibody validated in? Anti-Histone H4 antibody - ChIP Grade (ab7311) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF), ChIP in Cow, Human, Mouse, Saccharomyces cerevisiae samples. What is the molecular weight of Histone H4? Anti-Histone H4 - ChIP Grade (ab7311) specifically detects a band for Histone H4 (UniProt: P62805) at a molecular weight of 11kDa. Trusted by the scientific community Anti-Histone H4 - ChIP Grade (ab7311) was first used in a scientific publication in 2001 and has been cited over 100 times in peer-reviewed journals. Reviewed by scientists Anti-Histone H4 - ChIP Grade (ab7311) has over 10 independent reviews from customers.

Host

Rabbit

Reactivity

Cow, Human, Mouse, Saccharomyces cerevisiae

Application

ICC/IF, WB, ChIP, IHC-P

Platform ID

BAB395965461

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Histone H4 antibody - ChIP Grade
Cat. No.AB7311
HostRabbit
IsotypeIgG
ReactivityCow, Human, Mouse, Saccharomyces cerevisiae
ApplicationICC/IF, WB, ChIP, IHC-P
ClonalityPolyclonal
Concentration0.9 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. See full target information H4C1

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