Anti-Histone H4 antibody [EPR16599] - ChIP Grade,Abcam,AB177840

What is this antibody validated in? Anti-Histone H4 antibody [EPR16599] - ChIP Grade (ab177840) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF), ChIP, Peptide Array in Drosophila melanogaster, Human, Mouse, Rat, samples. What is the molecular weight of Histone H4? Anti-Histone H4 [EPR16599] - ChIP Grade (ab177840) specifically detects a band for Histone H4 (UniProt: P62805) at a molecular weight of 11kDa. Trusted by the scientific community Anti-Histone H4 [EPR16599] - ChIP Grade (ab177840) was first used in a scientific publication in 2014 and has been cited over 20 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EPR16599] also available for your convenience: ab177840, Alexa Fluor® 647 - ab207075 , HRP - ab208870 , Carrier free - ab232371 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Rat, Human, Drosophila melanogaster

Application

ICC/IF, WB, ChIP, PepArr, IHC-P

Platform ID

BAB020977955

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Histone H4 antibody [EPR16599] - ChIP Grade
Cat. No.AB177840
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human, Drosophila melanogaster
ApplicationICC/IF, WB, ChIP, PepArr, IHC-P
ClonalityMonoclonal
Clone NumberEPR16599
Concentration1.641 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. See full target information H4C1

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