Anti-Histone H4 antibody [EPR21213] - ChIP Grade,Abcam,AB223875

This product was made using synthetic libraries and phage display technology. This antibody is a recombinant chimeric antibody. Rabbit chimeric monoclonal antibody (Human Fab/ Rabbit Fc).

Host

Rabbit

Reactivity

Mouse, Cow, Human

Application

PepArr, ICC, WB, ChIP

Platform ID

BAB333484202

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Histone H4 antibody [EPR21213] - ChIP Grade
Cat. No.AB223875
HostRabbit
IsotypeIgG
ReactivityMouse, Cow, Human
ApplicationPepArr, ICC, WB, ChIP
ClonalityMonoclonal
Clone NumberEPR21213
Concentration0.563 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. See full target information H4C1

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