Anti-Hsd17b11 antibody,Abcam,AB224437

Host

Rabbit

Reactivity

Human

Application

IHC-P, ICC/IF, WB

Platform ID

BAB718566860

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Hsd17b11 antibody
Cat. No.AB224437
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIHC-P, ICC/IF, WB
ClonalityPolyclonal
Concentration0.1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human HSD17B11 aa 200 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma. See full target information HSD17B11

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