Anti-Human Aggrecan monoclonal antibody Anti-Human 100 µg,Reliatech,101-M213

This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with Human Aggrecan recombinant protein.

Host

Mouse

Reactivity

Human

Application

WB, IHC (P)

Platform ID

BAB495497893

Reliatech

Headquarters

Lindener Straße 15 38300 Wolfenbüttel Germany

Contact

Tel: +49 (0) 5331 - 8586987
Fax: +49 (0) 5331- 8586989

Product Specifications
Scientific Background
Synonyms

Specifications

NameAnti-Human Aggrecan monoclonal antibody Anti-Human 100 µg
Cat. No.101-M213
Accession NumberE7ENV9
HostMouse
IsotypeIgG2
ReactivityHuman
ApplicationWB, IHC (P)
Clone Number(#23A8)
Appearance/Formlyophilized
FormulationPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Regulatory StatusFor research use only

Scientific Background

Aggrecan, together with type II collagen, makes up to 90% of the dry weight of healthy cartilage. It hydrates the collagen network and thus provides cartilage with its properties of compressibility and elasticity. The N-terminal region of human Aggrecan (residues 20-675) consists of two globular domains (G1 and G2), flanking an interglobular domain (IGD). The IGD contains the cleavage sites for matrix metalloproteinases and aggrecanases.

Synonyms

ACAN; AGC1; SEDK; AGCAN; CSPG1; MSK16; CSPGCP

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