Anti-Human Angiostatin monoclonal antibody Anti-Human 100 µg,Reliatech,101-M220

This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with Human Kringle 1-3 recombinant protein.

Host

Mouse

Reactivity

Human

Application

WB

Platform ID

BAB683141574

Reliatech

Headquarters

Lindener Straße 15 38300 Wolfenbüttel Germany

Contact

Tel: +49 (0) 5331 - 8586987
Fax: +49 (0) 5331- 8586989

Product Specifications
Scientific Background
Synonyms

Specifications

NameAnti-Human Angiostatin monoclonal antibody Anti-Human 100 µg
Cat. No.101-M220
Accession NumberP00747
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationWB
Clone Number(#6F34)
Appearance/Formlyophilized
FormulationPBS
ReconstitutionCentrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
StorageLyophilized samples are stable for 2 years from date of receipt when stored at -70°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Regulatory StatusFor research use only

Scientific Background

Angiostatin, an internal fragment of plasminogen, is a potent inhibitor of angiogenesis, which selectively inhibits endothelial cell proliferation. Angiostatin potently inhibits tumor growth and can maintain metastatic and primary tumors in a dormant state. It is defined by a balance of proliferation and apoptosis of the tumor cells and is composed of plasminogen first four cringle structures. This molecule is generated by proteolytic cleavage of plasminogen.

Synonyms

Angiostatin

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