Anti-Human CD28 [Clone CD28.2] — Purifiedin vivoGOLD™ Functional Grade,Leinco,C2820
Host
Mouse
Reactivity
Human
Application
FC,in vivo,IP
Platform ID
BAB009179482
Leinco
Contact
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Product Specifications
Scientific Background
Specifications
NameAnti-Human CD28 [Clone CD28.2] — Purifiedin vivoGOLD™ Functional Grade
Cat. No.C2820
HostMouse
ReactivityHuman
ApplicationFC,in vivo,IP
Clone NumberCD28.2
Concentration≥ 2.0 mg/ml
Purity≥95% monomer by analytical SEC ⋅ >95% by SDS Page
Endotoxin Level< 1.0 EU/mg as determined by the LAL method
ShippingNext Day 2-8°C
FormulationThis monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
StorageFunctional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at ≤ -70°C. Avoid Repeated Freeze Thaw Cycles.
Scientific Background
CD28 is a 44 kD glycoprotein and a member of the Ig superfamily. In its capacity as a costimulatory receptor, CD28 produces co-stimulatory signals necessary for T cell activation and survival. CD28 is the only B7 receptor constitutively expressed on naive T cells. Without having this CD28/B7 interaction, T cells will fail to respond to their specific antigen when coming in contact with an MHC/antigen complex and thus, are said to be anergic.
Category Paths
- Products>Primary Antibodies>In Vivo Antibodies
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