Anti-Human CD28 [Clone CD28.2] — Purifiedin vivoPLATINUM™ Functional Grade,Leinco,C2880

Host

Mouse

Reactivity

Human

Application

FC,IP

Platform ID

BAB321685729

Leinco

Headquarters

410 Axminister Drive St. Louis, Missouri 63026

Contact

Tel: +1 (800) 538-1145,+1 (636) 230-9477
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Product Specifications
Scientific Background

Specifications

NameAnti-Human CD28 [Clone CD28.2] — Purifiedin vivoPLATINUM™ Functional Grade
Cat. No.C2880
HostMouse
ReactivityHuman
ApplicationFC,IP
Clone NumberCD28.2
Concentration≥ 2.0 mg/ml
Purity>98% by SDS Page
Endotoxin Level≤ 0.5 EU/mg as determined by the LAL method
ShippingNext Day 2-8°C
FormulationThis monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added.
StorageFunctional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at ≤ -70°C. Avoid Repeated Freeze Thaw Cycles.

Scientific Background

CD28 is a 44 kD glycoprotein and a member of the Ig superfamily. In its capacity as a costimulatory receptor, CD28 produces co-stimulatory signals necessary for T cell activation and survival. CD28 is the only B7 receptor constitutively expressed on naive T cells. Without having this CD28/B7 interaction, T cells will fail to respond to their specific antigen when coming in contact with an MHC/antigen complex and thus, are said to be anergic.

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