Anti-Human CD3 [Clone UCHT-1] — Purifiedin vivoGOLD™ Functional Grade,Leinco,C364
Host
Mouse
Reactivity
Human
Application
Depletion,FC,in vivo,IP,WB
Platform ID
BAB571710717
Leinco
Contact
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Product Specifications
Scientific Background
Specifications
NameAnti-Human CD3 [Clone UCHT-1] — Purifiedin vivoGOLD™ Functional Grade
Cat. No.C364
HostMouse
ReactivityHuman
ApplicationDepletion,FC,in vivo,IP,WB
Clone NumberUCHT-1
Concentration≥ 5.0 mg/ml
ImmunogenThis antibody was created by Professor Peter Beverley, a pioneer in creating hybridomas from mice immunized against human lymphocytes, with UCHT1 being one of the first successful fusions.
Purity≥95% monomer by analytical SEC ⋅ >95% by SDS Page
Endotoxin Level< 1.0 EU/mg as determined by the LAL method
ShippingNext Day 2-8°C
FormulationThis monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
StorageFunctional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at ≤ -70°C. Avoid Repeated Freeze Thaw Cycles.
Scientific Background
CD3ε is a 20kDa subunit of the TCR complex and is a transmembrane T-cell surface glycoprotein that belongs to the Ig superfamily. It is one of five polypeptide chains that form the TCR complex by associating with the CD3δ, γ and ζ chains, in addition to the TCR α/β or γ/δ chains. CD3 is involved in TCR signaling, enumeration of immunocompetent T-lymphocytes in peripheral blood, and signal transduction during antigen recognition.
Category Paths
- Products>Primary Antibodies>In Vivo Antibodies
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