Anti-Human CD4 [Clone OKT-4] — Purifiedin vivoPLATINUM™ Functional Grade,Leinco,C9205
Host
Mouse
Reactivity
Human
Application
ELISA,FC,in vivo,IP,WB
Platform ID
BAB321985585
Leinco
Contact
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Product Specifications
Scientific Background
Specifications
NameAnti-Human CD4 [Clone OKT-4] — Purifiedin vivoPLATINUM™ Functional Grade
Cat. No.C9205
HostMouse
ReactivityHuman
ApplicationELISA,FC,in vivo,IP,WB
Clone NumberOKT-4
ImmunogenHuman peripheral T cells
Purity≥98% monomer by analytical SEC ⋅ >95% by SDS Page
Endotoxin Level<0.5 EU/mg as determined by the LAL method
ShippingNext Day 2-8°C
FormulationThis monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
StorageFunctional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at ≤ -70°C. Avoid Repeated Freeze Thaw Cycles.
Scientific Background
CD4 is a 55 kD single-chain type I transmembrane glycoprotein and a member of the Ig superfamily. It is involved in the recognition of MHC class II molecules. Furthermore, CD4 is the primary receptor for HIV. CD4 initiates the early phase of T-cell activation via its association with the T-cell receptor complex and protein tyrosine kinase, Lck. In addition, CD4 functions as a mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system.
Category Paths
- Products>Primary Antibodies>In Vivo Antibodies
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