Anti-Human CD7 [Clone T3-3A1] — Purifiedin vivoGOLD™ Functional Grade,Leinco,C8400
Host
Mouse
Reactivity
Human
Application
FC,in vivo
Platform ID
BAB134941616
Leinco
Contact
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Product Specifications
Scientific Background
Specifications
NameAnti-Human CD7 [Clone T3-3A1] — Purifiedin vivoGOLD™ Functional Grade
Cat. No.C8400
HostMouse
ReactivityHuman
ApplicationFC,in vivo
Clone NumberT3-3A1
Concentration≥ 2.0 mg/ml
Purity≥95% monomer by analytical SEC ⋅ >95% by SDS Page
Endotoxin Level< 1.0 EU/mg as determined by the LAL method
ShippingNext Day 2-8°C
FormulationThis monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
StorageFunctional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at ≤ -70°C. Avoid Repeated Freeze Thaw Cycles.
Scientific Background
CD7 is a 40 kD type I transmembrane glycoprotein and is a member of the Ig superfamily. It plays a vital role in T-cell interactions, in adition to, T-cell/B-cell interaction during early lymphoid development, and has been shown to interact with PIK3R1. Functional studies indicate that crosslinking of the CD7 can stimulate transmembrane calcium flux in T cells. Lack of CD7 expression can help to diagnose T-cell lymphoproliferative disorders, such as mycosis fungoides/Sezary syndrome and adult T-cell leukemia/lymphoma.
Category Paths
- Products>Primary Antibodies>In Vivo Antibodies
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