Anti-Huntingtin antibody,Abcam,AB155942

Human HTT caspase cleavage sites generate fragment-specific forms of the protein. Caspase-3/7 has been shown to generate cleavage sites at animo acids 513 and 552. Caspase-2 cleaves at amino acid 552 and caspase-6 at amino acid 586.

Host

Rabbit

Reactivity

Mouse, Human

Application

WB, ELISA, ICC/IF, IHC

Platform ID

BAB408359509

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Huntingtin antibody
Cat. No.AB155942
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationWB, ELISA, ICC/IF, IHC
ClonalityPolyclonal
Concentration0.4 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human HTT aa 500-600 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide Constituents: PBS, 0.1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Huntingtin. May play a role in microtubule-mediated transport or vesicle function.. Huntingtin, myristoylated N-terminal fragment. Promotes the formation of autophagic vesicles. See full target information HTT

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