Anti-ICK antibody,Abcam,AB196964

Host

Rabbit

Reactivity

Mouse, Human, African green monkey

Application

WB

Platform ID

BAB284296559

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-ICK antibody
Cat. No.AB196964
HostRabbit
IsotypeIgG
ReactivityMouse, Human, African green monkey
ApplicationWB
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human CILK1. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Required for ciliogenesis (PubMed : 24797473). Phosphorylates KIF3A (By similarity). Involved in the control of ciliary length (PubMed : 24853502). Regulates the ciliary localization of SHH pathway components as well as the localization of IFT components at ciliary tips (By similarity). May play a key role in the development of multiple organ systems and particularly in cardiac development (By similarity). Regulates intraflagellar transport (IFT) speed and negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner and this regulation requires its kinase activity (By similarity). See full target information CILK1

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.