Anti-IDH1 antibody [C12],Abcam,AB239606

Host

Mouse

Reactivity

Human, Pig

Application

IHC-P, WB

Platform ID

BAB972090168

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-IDH1 antibody [C12]
Cat. No.AB239606
HostMouse
IsotypeIgG2a
ReactivityHuman, Pig
ApplicationIHC-P, WB
ClonalityMonoclonal
Clone NumberC12
ImmunogenRecombinant Fragment Protein within Human IDH1 aa 50-350. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A/G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Catalyzes the NADP(+)-dependent oxidative decarboxylation of isocitrate (D-threo-isocitrate) to 2-ketoglutarate (2-oxoglutarate), which is required by other enzymes such as the phytanoyl-CoA dioxygenase (PubMed : 10521434, PubMed : 19935646). Plays a critical role in the generation of NADPH, an important cofactor in many biosynthesis pathways (PubMed : 10521434). May act as a corneal epithelial crystallin and may be involved in maintaining corneal epithelial transparency (By similarity). See full target information IDH1

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