Anti-IDH3A antibody,Abcam,AB154886

Host

Rabbit

Reactivity

Zebrafish, Mouse, Rat, Human

Application

IHC-P, WB

Platform ID

BAB159833801

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-IDH3A antibody
Cat. No.AB154886
HostRabbit
IsotypeIgG
ReactivityZebrafish, Mouse, Rat, Human
ApplicationIHC-P, WB
ClonalityPolyclonal
Concentration0.63 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial aa 100 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Catalytic subunit of the enzyme which catalyzes the decarboxylation of isocitrate (ICT) into alpha-ketoglutarate. The heterodimer composed of the alpha (IDH3A) and beta (IDH3B) subunits and the heterodimer composed of the alpha (IDH3A) and gamma (IDH3G) subunits, have considerable basal activity but the full activity of the heterotetramer (containing two subunits of IDH3A, one of IDH3B and one of IDH3G) requires the assembly and cooperative function of both heterodimers. See full target information Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

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