Anti-IGF2 antibody,Abcam,AB9574
What is this antibody validated in? Anti-IGF2 antibody (ab9574) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB), ELISA. Trusted by the scientific community Anti-IGF2 (ab9574) was first used in a scientific publication in 2002 and has been cited over 100 times in peer-reviewed journals. Reviewed by scientists Anti-IGF2 (ab9574) has over 20 independent reviews from customers.
Host
Rabbit
Application
WB, sELISA
Platform ID
BAB036070707
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data The insulin-like growth factors possess growth-promoting activity (By similarity). Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF2 is influenced by placental lactogen. Also involved in tissue differentiation. In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver (Probable). Acts as a ligand for integrin which is required for IGF2 signaling (PubMed : 28873464). Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation (By similarity). Inhibits myoblast differentiation and modulates metabolism via increasing the mitochondrial respiration rate (By similarity).. Preptin undergoes glucose-mediated co-secretion with insulin, and acts as a physiological amplifier of glucose-mediated insulin secretion. Exhibits osteogenic properties by increasing osteoblast mitogenic activity through phosphoactivation of MAPK1 and MAPK3. See full target information IGF2
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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