Anti-IGFBP3 antibody [RM0096-11B16],Abcam,AB86461

ab86461 was produced from a hybridoma (mouse myeloma fused with spleen cells from an immunized rat).

Host

Rat

Reactivity

Human

Application

WB

Platform ID

BAB348876810

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-IGFBP3 antibody [RM0096-11B16]
Cat. No.AB86461
HostRat
IsotypeIgG2
ReactivityHuman
ApplicationWB
ClonalityMonoclonal
Clone NumberRM0096-11B16
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Mouse Igfbp3.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationConstituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R. Promotes testicular germ cell apoptosis. See full target information Igfbp3

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.