Anti-IL-1 beta antibody,Abcam,AB18955
This product is manufactured by BioVision, an Abcam company and was previously called 5129 Anti-Murine IL-1β Polyclonal Antibody. 5129-100 is the same size as the 100 µg size of ab18955. The antibody solution should be gently mixed before use.
Host
Rabbit
Reactivity
Mouse
Application
WB, Neutralization
Platform ID
BAB100051246
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. Involved in transduction of inflammation downstream of pyroptosis : its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore. See full target information Il1b
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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