Anti-IL-1 beta antibody [EPR16805-15],Abcam,AB234437
What is this antibody validated in? Anti-IL-1 beta antibody [EPR16805-15] (ab234437) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunocytochemistry/immunofluorescence (ICC/IF) in Mouse, Rat samples. What is the molecular weight of IL-1 beta? Anti-IL-1 beta [EPR16805-15] (ab234437) specifically detects a band for IL-1 beta (UniProt: P10749) at a molecular weight of 30kDa. Trusted by the scientific community Anti-IL-1 beta [EPR16805-15] (ab234437) was first used in a scientific publication in 2019 and has been cited over 60 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EPR16805-15] also available for your convenience: ab234437, Carrier free - ab244612 , Carrier free - ab254195 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .
Host
Rabbit
Reactivity
Mouse, Rat
Application
Flow Cyt (Intra), IP, ICC/IF, WB
Platform ID
BAB287594975
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. Involved in transduction of inflammation downstream of pyroptosis : its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore. See full target information Il1b
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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