Anti-IL-2 Receptor alpha antibody [PC61.5] - Low endotoxin, Azide free,Abcam,AB210333

Endotoxin Level: Less than or equal to 0.01 EU/μg, as determined by the LaL assay. ab210333 is used as a marker for T cells, B cells and dendritic cell subsets. Expression of CD25, CD4 and the transcription factor Foxp3 is regarded as a phenotypic signature for Treg cells. As such, this antibody is widely used for depletion of Treg cells in vivo, as well as to distinguish Treg cells from naïve or conventional T cells which are CD25-.

Host

Rat

Reactivity

Mouse

Application

Flow Cyt, FuncS, IHC-Fr, IP

Platform ID

BAB664681473

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-IL-2 Receptor alpha antibody [PC61.5] - Low endotoxin, Azide free
Cat. No.AB210333
HostRat
IsotypeIgG1
ReactivityMouse
ApplicationFlow Cyt, FuncS, IHC-Fr, IP
ClonalityMonoclonal
Clone NumberPC61.5
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Constituents: 0.87% Sodium chloride, 0.12% Sodium dihydrogen phosphate
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. See full target information Il2ra

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