Anti-IL-34 antibody [1D12],Abcam,AB101443

Host

Mouse

Reactivity

Human

Application

ICC/IF, Flow Cyt, WB

Platform ID

BAB978087288

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-IL-34 antibody [1D12]
Cat. No.AB101443
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationICC/IF, Flow Cyt, WB
ClonalityMonoclonal
Clone Number1D12
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human IL34 aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1. See full target information IL34

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