Anti-IL-5RA antibody - C-terminal,Abcam,AB198808
Host
Rabbit
Reactivity
Human
Application
IHC-P
Platform ID
BAB040968355
Abcam
Contact
Tel: +44 (0)1223 696000
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Product Specifications
Scientific Background
Specifications
NameAnti-IL-5RA antibody - C-terminal
Cat. No.AB198808
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIHC-P
ClonalityPolyclonal
Concentration2.4 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human IL5RA. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Cell surface receptor that plays an important role in the survival, differentiation, and chemotaxis of eosinophils (PubMed : 9378992). Acts by forming a heterodimeric receptor with CSF2RB subunit and subsequently binding to interleukin-5 (PubMed : 1495999, PubMed : 22528658). In unstimulated conditions, interacts constitutively with JAK2. Heterodimeric receptor activation leads to JAK2 stimulation and subsequent activation of the JAK-STAT pathway (PubMed : 9516124). See full target information IL5RA
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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