Anti-IL3RA/CD123 antibody [IL3RA/1531] - BSA and Azide free,Abcam,AB268196

ab268196 is the carrier-free version of ab268075 . Conjugation ready Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications. Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Host

Mouse

Reactivity

Human

Application

IHC-P, Protein Array

Platform ID

BAB917105309

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-IL3RA/CD123 antibody [IL3RA/1531] - BSA and Azide free
Cat. No.AB268196
HostMouse
IsotypeIgG2b
ReactivityHuman
ApplicationIHC-P, Protein Array
ClonalityMonoclonal
Clone NumberIL3RA/1531
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human IL3RA aa 1-200. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A/G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Cell surface receptor for IL3 expressed on hematopoietic progenitor cells, monocytes and B-lymphocytes that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells (PubMed : 10527461). Ligand stimulation rapidly induces hetrodimerization with IL3RB, phosphorylation and enzyme activity of effector proteins such as JAK2 and PI3K that play a role in signaling cell proliferation and differentiation. Activation of JAK2 leads to STAT5-mediated transcriptional program (By similarity). See full target information IL3RA

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