Anti-IRF2BP2 antibody,Abcam,AB124163

Host

Rabbit

Reactivity

Human, Mouse

Application

WB

Platform ID

BAB547015451

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-IRF2BP2 antibody
Cat. No.AB124163
HostRabbit
IsotypeIgG
ReactivityHuman, Mouse
ApplicationWB
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human IRF2BP2. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities (PubMed : 12799427). Represses the NFAT1-dependent transactivation of NFAT-responsive promoters (PubMed : 21576369). Acts as a coactivator of VEGFA expression in cardiac and skeletal muscles (PubMed : 20702774). Plays a role in immature B-cell differentiation (PubMed : 27016798). See full target information IRF2BP2

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