Anti-IRSp53 antibody - C-terminal,Abcam,AB15697

This antibody is expected to recognise the human isoform 1 only of this protein.

Host

Goat

Reactivity

Human, Mouse, Dog

Application

WB

Platform ID

BAB672677633

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-IRSp53 antibody - C-terminal
Cat. No.AB15697
HostGoat
IsotypeIgG
ReactivityHuman, Mouse, Dog
ApplicationWB
ClonalityPolyclonal
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human Brain-specific angiogenesis inhibitor 1-associated protein 2 aa 500-550. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.3 Preservative: 0.02% Sodium azide Constituents: 0.5% BSA, 0.05% Tris buffered saline
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation. Plays a role in the reorganization of the actin cytoskeleton in response to bacterial infection. Participates in actin bundling when associated with EPS8, promoting filopodial protrusions. See full target information Brain-specific angiogenesis inhibitor 1-associated protein 2

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