Anti-Iba1 antibody [EPR16588] - Microglia marker – Chicken IgY (Chimeric),Abcam,AB318302

This chicken monoclonal chimeric antibody has been engineered from a RabMAb parent antibody ( ab178846 ). By necessity, some rabbit sequence is retained as part of the variable domain. When multiplexing with other rabbit-derived antibodies, using cross absorbed Fc-reactive secondary antibodies are recommended. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Chicken

Reactivity

Human, Mouse, Rat

Application

ICC/IF, IHC-Fr, IHC-P

Platform ID

BAB783746823

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Iba1 antibody [EPR16588] - Microglia marker – Chicken IgY (Chimeric)
Cat. No.AB318302
HostChicken
IsotypeIgY
ReactivityHuman, Mouse, Rat
ApplicationICC/IF, IHC-Fr, IHC-P
ClonalityMonoclonal
Clone NumberEPR16588
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Thiophilic Resin
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation. See full target information AIF1 Additional targets Aif1

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